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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3310f3426ddbc0a22d6011163a74ce15a13327bbee3a2a07824066a9d63dc4c5' 
  AND token = 'cG32L1t/GKLOAKlS1RquqR+C8FddIK7h3Ls+CBCZdq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}