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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e418e75e689c7a78b1577654ad557ec4cc4a11f97fe7f4aedd3621d269b2fe43' 
  AND token = 'ky0nFr2yZtc65RnmbDtcLdygS33w9HjIejz1NZtb2xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}