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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f72007b808d3357393ab7c72d7af89f0a44950ea55a8ebcc4ba5a4177698581' 
  AND token = 'XdHFYVR6rYJqFoKU2fEYLJyoKH6kOvqkLPWyW3uGr2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}