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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a100c52c3ed173f27ac4ef6563ce2dd1763698e19346d37e2bc05a131df30cf3' 
  AND token = 'w+8mo3nx2LXnrenS1a4hQVd5F7mvU0VjCM/pZR/y6UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}