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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db95a3053fd30bbf1cd2194ad314c7d58a75a6936e78b7ecd0258291345a9d1' 
  AND token = 'Hy5z1Q6/woW+7fj1JlpNt3WRrIvOGz+RIFScF6Q0xPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}