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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0674218a1b6c3e5e405d481afc3da0e129d7325bd301c3bedefce401c1be78' 
  AND token = 'EHTvm5BfBD5ibIKPcOQqV0UAeaoBDddddEOEojGoLAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}