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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709ff699afc764c9dc2ed1f62de39af4f7de9eadd812fcfdd108c09b1e4a2342' 
  AND token = '8U6v0frdp+Ooh8anIguiwWL8bylF2mXQI6qNucKXd2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}