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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8ebaf53c83fc7387567a63784250d29e274caa9717c4e95b42a8698a5c5d20' 
  AND token = 'HI8ACZNuX31btgWJQfE3BCXIoJ3oc48SyMU7uviR3tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}