SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37db4c815f6ebd1c29dcd2b355065516486f3f0e6a6061e0e573ecd86f1a788' 
  AND token = 'aUXg7MmLoDA0evoUQYaINPLkWRIOdRPNvI1ppc/bbd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}