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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da52b1b529dcf0c260a8618135c8df4156787f0ff7c595d56ae2158235b8dfa7' 
  AND token = '48kku+EN25h8zVSrnPJWcWs0TOqJhC+C2cPmb9QnSeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}