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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39a53a0cc00ecddf532f779fcd8d902e0b2d2e96ae644478dd89640e7f4cf6d' 
  AND token = 'ucbCM0pa/MC05fUe06IzqdDLcslItfhkoTQpfv1jOhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}