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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246cb450ce59ac85e181d655f3dd8806ae641ef4ffd3f3654a27a71a0e91ac7e' 
  AND token = 'cNgnZ23PsgcsBqfICtHmT+h9qad9AL8n2NUJK2ABFD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}