SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab6d9fd03036b2a485c2ca5789a9843d5ad6d1a4927aca090356b7bd527a3138' 
  AND token = 'DbXcG+5BhZ8Ekg54OAfaOZnT9gQWG7kTRqb9Ya43yi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}