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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd747d9622439b0518d4daff36831297c7693279f21463e498e63f00499d9c0b6' 
  AND token = 'FRpma60NdBJXgRVWRP5V5fhmE6Lg3L111ityN6T9Pqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}