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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bf2e8068ca74aaa646bbfb008afee947a3a7a1bb958266873f4fef3421420b' 
  AND token = 'mfr9kwx/1D3P6VYDip+yL2qAI8Ya9PQPNwehfdvzKEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}