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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64fe4963aed5708eb161c4ac197232aeaab6fe06fab9e59907a8a51fa28b6276' 
  AND token = 'tR5VMOz1lCxS0laIxK19LBKEnSGyMQzIyWI4XIFBUJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}