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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72893ad9c6158fcde59af94d0f4224d75d0a6957cbd5eb81ec6ae749287cef90' 
  AND token = 'ABxqQgsoD4A657EuQ/JNaSltM353EwZxfSbe7MAHQ3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}