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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0d26813ba8fd907caa3b043a9c9fcf8c43945001f4b7dac1e937b1d27658c2' 
  AND token = 'SHIxDb5UoLMw+qNZQNK49ztsoujWZFl5xcyM9esMXxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}