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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dfd98b27d36f67f5faaec9ea49a83e16a672d13b2abb9f2880b2c58289e9955' 
  AND token = 'ArX7vC+RoE7/CPbk/SsY9jeH7WTRWd0No3IRg+dFzI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}