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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec18247c31e5baf1c0b0ab35ca41c2f2b99b0759a6aac15f59093e04ec7006d9' 
  AND token = 'wjY8R3hRea17Kmt+sBROWxIhpdw6DxPpOWY9MtefmSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}