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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb8a0bfe0b4a31a39fb981e7a432469934d24823b1010677f6cbcff2b497667' 
  AND token = '/Ez7DLqDBXOv3WYi9LvMje05P141GWmpmhANyU0pXh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}