SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd44fa1928a163a05831069017bb9dad3e621256b397a27d91098610684782588' 
  AND token = 'Pir3T4uIvoknfjxPbJIrqiRMx4g/h8SSbQXCoHr4bCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}