SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ceee2fb0d7821475e9436e7e71d623e561d0b855534efac8ebb387a0f2181e' 
  AND token = 'm833KIndKnKgQgJn205KsPDEx4uPWb+D320y2fgZ02Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}