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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d96ac58a53c98f4f52dce656f5dd424f28cd7220f51f03cfa7ec56e5982870' 
  AND token = 'QrzzRMeJO5+obKRy3FXFsqOuQ8G733ml3k54JSOi8DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}