SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a4d773b3db599821a5e1588fc9b8914dbcc982292d1a52d0a43cf6ee36fbbf' 
  AND token = 'DMf1RaAypivXjhNBWSVKNlLUFsF7C+g+MK8a9uGtGqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}