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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757ff8d76129a0c216f928180bed27d8076dc0b18486dc71eca670de6b2df2f3' 
  AND token = 'o6C55fuVcGE57N7I5f0q1vodCCTf6AI7f1Aj3MidGe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}