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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d75c69cc9b1823e68d83ae045bf41a2a7a73380e9537652d4a71fcb4fe1440' 
  AND token = 'cWDNwERcc2qo3Rk4Lq7IZCgWX7HJ4fzVWim+pUoYQlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}