SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec1e60cba69b2c23504951d732528153cff8dfb8d32fcd4726c3be749ddd3ac' 
  AND token = 'skSL5WH0CMpqUAfewJJ/F/UkpLHdnP7ySBFElqzqFrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}