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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb85b8d54f06ebe6374b14fbda9b69d77481b142cc728e65df3cd7803c9b9a2' 
  AND token = 'PcHhX2GEhTParzUh7d+CqH3V/w3cr8qyEXlQgNcN3eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}