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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9609ca7e5b3a4fe81ae66a11f8f18d7b3491de5204d9109fad7eca8b4da54c' 
  AND token = 'Mxyq5/XrbHkPBAubzlduYtIB2vK9ac560H/wCZoJTWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}