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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f28c8d5bde19f981fbb750729caaadeaa024714de59e6f34848ca43e44e7c1e' 
  AND token = 'xo8EJNPq7IrzxvnhrNf7V81EIIzUj3CC6d8EGCz1YXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}