SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0d9666b7af816818959bb5a28d2aa75ae4f6460bdd0d83bbe3788180a6f1ec' 
  AND token = '4eAwAs/pNtkzoGiyf4n28YZt0f9Dl19lBr1rCWf2XLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}