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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e62e88ac77ebcf7d35399e667b4115d0240546e2605ee68229d4077024e9c6' 
  AND token = 'yDgMZn8Q1mEu4WUgpHZmHUvwAxTyoNR2IQCtW9QNQUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}