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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d88c7081315eb7b62d93f3ca42d24a5d4a438286f6857304139fa762ebdb6b7' 
  AND token = 'iLQPLwQ9siMdiOniGmLP52qP1zkE+wawIWYpclwU7jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}