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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a5aa12706c473684a07a21e05beb976966c89a5805492addf5d81364b364a6' 
  AND token = '1dFb/Xd8SfB30Z0ECESu6KZpP9kiCFYS9JW+OyJ/X/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}