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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7201c7b907a2d65f8b20451277bbcb437fd956f8d8ddc0d0ec7b085089d38c32' 
  AND token = 'ugA3vFWCE1s1xz8GW7guQSp0MisI6qfs+dGU90759wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}