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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d782956370033c02a17456136ccb0aa2b998a48afa80b68385d08f6d307dc2' 
  AND token = 'fhuo+ut29AI2bWaJBj458QAKAasXsD8kCkN8Bwsgv3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}