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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837b5ff4fb109a9df2809bdef36797583693f30336ac8100c463fa8ed860c8ad' 
  AND token = 'MxO5kFNO1z2uEA54jq1wBcuOfvDhrhlXSv7llgsO/T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}