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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41610057b016d560c9c935400995cc0821a061a89077e2b179bee78e246e3ac' 
  AND token = 'PYAx3jt73s2xnZ974RdukuyUgCTdsfqYifA9ykoax9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}