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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0599c28470a9d333555198d66015de8a27ad83b82382e380ce8f171687f2cf0' 
  AND token = 'LzPotvOmRxUgm/kIEs6T/GMYa4ATJJnxBY9V0nNIyl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}