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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081e790f94e7b1ca52005b4c72da7c80ca0a0801e975d5f6e01b75bebb0dd291' 
  AND token = 's3DvALYpTv+xOuBabqFqjb2+/fNncimnPjjS5FjNlug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}