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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b251f90e8ff21fdadf7483a0271c1b24e721caadebfccf94d248048d4aabf436' 
  AND token = 'cEtVXofCDVVr2i8Oqp3Fynmhoik1vbFFfbphE9TvpAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}