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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e04f453772fe20eef7c400c1591654295dde0d652db39d3775b66f23685048' 
  AND token = 'DbPtz4x9VTdXXUBxA+1kHNHnwfmU+lOtrmqp6DZFnkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}