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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5c59bfa3ffeb9c226c1ca6821d296968f26264316ed338cbc3286b28b09b58' 
  AND token = 'PqNgiDFFNQf2Duuk2syAFr2cYpMA5gfpHIyjhSgQ9hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}