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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d38f200d98373cc00bd3ca6bb1607a3303de20f334a4ae8b8343be2222c6d7' 
  AND token = 'OFYCq/aioMEShcQIn4atfhm/pPXdzJ3Xg+ANTx7lYtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}