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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04eba94e4953304a145804b6667c44dd6301b46cea975e7731989e4b4c580bb4' 
  AND token = '1rRVmh6JBDX7tsAASPnzJmLSuFVqmBBBwEwfA6hacwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}