SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '083aecc91a465f9859aa82aa1e7c9894cae986d6645add86bd4f49c501c55b5c' 
  AND token = 'ZxKVFmcKSE1EQVDMeKI1dwitslJHvramSQ2DVdWtBUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}