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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3d28cbf6f60bcf89039d6d978958bbc140e8d8a2f7660940d668475f1e6528' 
  AND token = '+E7/kCtPDfNWQyd3K+ZLnw+1rT+Fq/GFe0oTNcu1KkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}