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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97aaed971ad1cb3aa426486d1a790a7a9c318724f67fe81f69b59b6afae07fe0' 
  AND token = 'KjPkKHWP7ZG2CTuHsvx3yLYG2V49TBJVivb9F1YIMWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}