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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c67f2f3d5bb97d7d0b7db1d64d2b0eb9976682e21cbe5370af3f295e87fcdf' 
  AND token = 'NIe2dLn1E+GspjDn+YUCWiwnEF4nzhpsyjp/fIVFL34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}